Assessment of glomerular filtration rate measurement with plasma sampling: a technical review.

Murray, Anthony W; Barnfield, Mark C; Waller, Michael L; Telford, Tania; Peters, A Michael

Murray, Anthony W; Barnfield, Mark C; Waller, Michael L; Telford, Tania; Peters, A Michael.

Afiliação

Murray AW; Department of Medical Physics, St. James's University Hospital, Leeds, United Kingdom. awm@medphysics.leeds.ac.uk

J Nucl Med Technol ; 41(2): 67-75, 2013 Jun.

Article em En | MEDLINE | ID: mdl-23658207

ABSTRACT

ABSTRACT

This article reviews available radionuclide-based techniques for glomerular filtration rate (GFR) measurement, focusing on clinical indications for GFR measurement, ideal GFR radiopharmaceutical tracer properties, and the 2 most common tracers in clinical use. Methods for full, 1-compartment, and single-sample renal clearance characterization are discussed. GFR normalization and the role of GFR measurement in chemotherapy dosing are also considered.

Assuntos

Análise Química do Sangue/métodos; Taxa de Filtração Glomerular; Testes de Função Renal/métodos; Antineoplásicos/sangue; Antineoplásicos/farmacocinética; Antineoplásicos/farmacologia; Humanos; Traçadores Radioativos

Palavras-chave

GFR measurement; GFR normalization; glomerular filtration rate; radiopharmaceutical tracer; technical review

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise Química do Sangue / Taxa de Filtração Glomerular / Testes de Função Renal Limite: Humans Idioma: En Revista: J Nucl Med Technol Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google