Quantification of intraocular IFNgamma and IgG in cataract and diabetes.

ABSTRACT

The anterior eye chamber is called the immunologically privileged place. The inflammatory disturbances in the interior of the eye chamber are characterised primarly by the changes of the IFN-gamma, IgG and IL-4 concentration and appearance of the oligoclonal IgG. In type I diabetes, there are antibodies to the beta cells of the pancreas, IgG class (among others such as antiretinal antibodies) and they are also found in preretinal membranes of diabetics. In type II there are IgG antibodies to insulin receptors.