Cloning and heterologous expression of the thioviridamide biosynthesis gene cluster from Streptomyces olivoviridis.
Appl Environ Microbiol
; 79(22): 7110-3, 2013 Nov.
Article
em En
| MEDLINE
| ID: mdl-23995943
ABSTRACT
Thioviridamide is a unique peptide antibiotic containing five thioamide bonds from Streptomyces olivoviridis. Draft genome sequencing revealed a gene (the tvaA gene) encoding the thioviridamide precursor peptide. The thioviridamide biosynthesis gene cluster was identified by heterologous production of thioviridamide in Streptomyces lividans.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeos Cíclicos
/
Família Multigênica
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Streptomyces lividans
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Genes Bacterianos
/
Antibacterianos
Idioma:
En
Revista:
Appl Environ Microbiol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Japão