Globus pharyngeus: effectiveness of treatment with proton pump inhibitors and gabapentin.
Ann Otol Rhinol Laryngol
; 122(8): 492-5, 2013 Aug.
Article
em En
| MEDLINE
| ID: mdl-24027858
ABSTRACT
OBJECTIVES:
This study was performed to investigate the effectiveness of treatment of globus pharyngeus with proton pump inhibitors, gabapentin, or both.METHODS:
The subjects all presented with globus pharyngeus during the years 2006 to 2011. The inclusion criteria included a chief (primary) complaint of globus pharyngeus; a trial of proton pump inhibitor therapy for at least 2 months and/or a trial of gabapentin for at least 2 weeks; and at least 1 follow-up visit. We reviewed 331 charts; 87 patients met the criteria. The response to treatment was graded as none, partial, or complete.RESULTS:
Seventy-seven percent of all patients had improvement. Sixty-seven percent of patients had a partial or complete response from aggressive reflux management. Sixty-six percent of patients who had a trial of gabapentin reported improvement. Eight of 14 patients who did not improve with aggressive reflux management improved with gabapentin.CONCLUSIONS:
A majority of patients with globus pharyngeus can be helped by treating reflux or neuralgia. A trial of gabapentin should be considered for patients who do not respond or only partially respond to reflux management.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos de Deglutição
/
Faringite
/
Transtornos de Sensação
/
Ácidos Cicloexanocarboxílicos
/
Inibidores da Bomba de Prótons
/
Ácido gama-Aminobutírico
/
Aminas
/
Analgésicos
Tipo de estudo:
Observational_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Ann Otol Rhinol Laryngol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos