bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia.
J Exp Med
; 162(6): 2175-9, 1985 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-2415665
ABSTRACT
Southern blot analysis detected a bcr gene rearrangement within leukemic cells of a Philadelphia chromosome-negative chronic myelocytic leukemia (CML) patient that led to transcription of a novel 7.3 kb bcr RNA species. Participation of the c-abl oncogene in this genomic recombination could be ruled out by in situ hybridization studies and Northern blot analysis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oncogenes
/
Leucemia Mieloide
/
Cromossomos Humanos 21-22 e Y
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Exp Med
Ano de publicação:
1985
Tipo de documento:
Article