Aberrantly spliced HTT, a new player in Huntington's disease pathogenesis.

Gipson, Theresa A; Neueder, Andreas; Wexler, Nancy S; Bates, Gillian P; Housman, David

Gipson, Theresa A; Neueder, Andreas; Wexler, Nancy S; Bates, Gillian P; Housman, David.

Afiliação

Gipson TA; Koch Institute for Integrative Cancer Research; Massachusetts Institute of Technology; Cambridge, MA USA.
Neueder A; Department of Medical and Molecular Genetics; King's College London; London, UK.
Wexler NS; Hereditary Disease Foundation; New York, NY USA; Department of Neurology and Psychiatry; Columbia University; New York, NY USA.
Bates GP; Department of Medical and Molecular Genetics; King's College London; London, UK.
Housman D; Koch Institute for Integrative Cancer Research; Massachusetts Institute of Technology; Cambridge, MA USA.

RNA Biol ; 10(11): 1647-52, 2013 Nov.

Article em En | MEDLINE | ID: mdl-24256709

Assuntos

Doença de Huntington/genética; Proteínas Mutantes/genética; Proteínas do Tecido Nervoso/genética; Proteínas Nucleares/genética; Splicing de RNA; Animais; Humanos

Palavras-chave

HTT exon 1; Huntington's disease; SRSF6; huntingtin fragment; mis-splicing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Splicing de RNA / Doença de Huntington / Proteínas Mutantes / Proteínas do Tecido Nervoso Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: RNA Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2013 Tipo de documento: Article

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