Oncologic issues and kidney transplantation: a review of frequency, mortality, and screening.
Adv Chronic Kidney Dis
; 21(1): 106-13, 2014 Jan.
Article
em En
| MEDLINE
| ID: mdl-24359993
ABSTRACT
Kidney transplant recipients are at increased risk for development of malignancy compared with the general population, and malignancies occur at an earlier age. This increased risk, as expressed by the standard incidence ratio (SIR), varies widely, but it is highest in malignancies triggered by oncogenic viruses. For other cancers, this increased risk is the direct consequence of immunosuppressants promoting tumor growth and lowering immune system tumor surveillance. In this review, we briefly discuss the common malignancies with increased risk after kidney transplantation, explore the pros and cons associated with screening, and summarize current prevention and treatment recommendations.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Rim
/
Hospedeiro Imunocomprometido
/
Imunossupressores
/
Falência Renal Crônica
/
Neoplasias
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Screening_studies
Limite:
Female
/
Humans
Idioma:
En
Revista:
Adv Chronic Kidney Dis
Assunto da revista:
NEFROLOGIA
Ano de publicação:
2014
Tipo de documento:
Article