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Enhanced flowType/RchyOptimyx: a BioConductor pipeline for discovery in high-dimensional cytometry data.
O'Neill, Kieran; Jalali, Adrin; Aghaeepour, Nima; Hoos, Holger; Brinkman, Ryan R.
Afiliação
  • O'Neill K; Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada, Bioinformatics Graduate Program, University of British Columbia, Vancouver, BC V6T 1Z3, Canada, Max-Planck-Institut fur Informatik, Saarland University, 66123, Saarbrucken, Germany, Departments of Computer Science and Departments of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Bioinformatics ; 30(9): 1329-30, 2014 May 01.
Article em En | MEDLINE | ID: mdl-24407226
ABSTRACT
We present a significantly improved version of the flowType and RchyOptimyx BioConductor-based pipeline that is both 14 times faster and can accommodate multiple levels of biomarker expression for up to 96 markers. With these improvements, the pipeline is positioned to be an integral part of data analysis for high-throughput experiments on high-dimensional single-cell assay platforms, including flow cytometry, mass cytometry and single-cell RT-qPCR.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citometria de Fluxo Idioma: En Revista: Bioinformatics Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citometria de Fluxo Idioma: En Revista: Bioinformatics Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Canadá