The effect of prenatal pravastatin treatment on altered fetal programming of postnatal growth and metabolic function in a preeclampsia-like murine model.

McDonnold, Mollie; Tamayo, Esther; Kechichian, Talar; Gamble, Phyllis; Longo, Monica; Hankins, Gary D V; Saade, George R; Costantine, Maged M

The effect of prenatal pravastatin treatment on altered fetal programming of postnatal growth and metabolic function in a preeclampsia-like murine model.

McDonnold, Mollie; Tamayo, Esther; Kechichian, Talar; Gamble, Phyllis; Longo, Monica; Hankins, Gary D V; Saade, George R; Costantine, Maged M.

Afiliação

McDonnold M; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.
Tamayo E; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.
Kechichian T; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.
Gamble P; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.
Longo M; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.
Hankins GD; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.
Saade GR; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.
Costantine MM; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.

Am J Obstet Gynecol ; 210(6): 542.e1-7, 2014 Jun.

Article em En | MEDLINE | ID: mdl-24412113

Assuntos

Glicemia/metabolismo; Desenvolvimento Fetal/efeitos dos fármacos; Insulina/sangue; Camundongos/crescimento & desenvolvimento; Pravastatina/uso terapêutico; Pré-Eclâmpsia/tratamento farmacológico; Análise de Variância; Animais; Área Sob a Curva; Peso Corporal; Proteínas de Ciclo Celular; Modelos Animais de Doenças; Feminino; Masculino; Camundongos/metabolismo; Pravastatina/farmacologia; Pré-Eclâmpsia/sangue; Pré-Eclâmpsia/induzido quimicamente; Gravidez; Receptores Acoplados a Proteínas G; Receptor 1 de Fatores de Crescimento do Endotélio Vascular

Palavras-chave

fetal programming; metabolic; pravastatin; preeclampsia; weight

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / Glicemia / Pravastatina / Desenvolvimento Fetal / Insulina / Camundongos Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Revista: Am J Obstet Gynecol Ano de publicação: 2014 Tipo de documento: Article

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