Analgesic efficacy of caudal dexamethasone combined with ropivacaine in children undergoing orchiopexy.
Br J Anaesth
; 112(5): 885-91, 2014 May.
Article
em En
| MEDLINE
| ID: mdl-24491414
ABSTRACT
BACKGROUND:
Epidural administration of dexamethasone might reduce postoperative pain in adults. We evaluated whether a caudal block of 0.1 mg kg(-1) dexamethasone combined with ropivacaine improves analgesic efficacy in children undergoing day-case orchiopexy.METHODS:
This randomized, double-blind study included 80 children aged 6 months to 5 yr who underwent day-case, unilateral orchiopexy. Patients received either 1.5 ml kg(-1) of 0.15% ropivacaine (Group C) or 1.5 ml kg(-1) of 0.15% ropivacaine in which dexamethasone of 0.1 mg kg(-1) was mixed (Group D) for caudal analgesia. Postoperative pain scores, rescue analgesic consumption, and side-effects were evaluated 48 h after operation.RESULTS:
Postoperative pain scores at 6 and 24 h post-surgery were significantly lower in Group D than in Group C. Furthermore, the number of subjects who remained pain free up to 48 h after operation was significantly greater in Group D [19 of 38 (50%)] than in Group C [four of 37 (10.8%); P<0.001]. The number of subjects who received oral analgesic was significantly lower in Group D [11 of 38 (28.9%)] than in Group C [20 of 37 (54.1%); P=0.027]. Time to first oral analgesic administration after surgery was also significantly longer in Group D than in Group C (P=0.014). Adverse events after surgery including vomiting, fever, wound infection, and wound dehiscence were comparable between the two groups.CONCLUSIONS:
The addition of dexamethasone 0.1 mg kg(-1) to ropivacaine for caudal block can significantly improve analgesic efficacy in children undergoing orchiopexy. Clinical trial registration NCT01604915.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dexametasona
/
Anestésicos Combinados
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Orquidopexia
/
Amidas
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Anestesia Caudal
/
Anestésicos Locais
/
Anti-Inflamatórios
Tipo de estudo:
Clinical_trials
/
Observational_studies
Limite:
Child, preschool
/
Humans
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Infant
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Male
Idioma:
En
Revista:
Br J Anaesth
Ano de publicação:
2014
Tipo de documento:
Article