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Synthesis and biological evaluation of novel benzamide derivatives as potent smoothened antagonists.
Wu, Tian-Ming; Wang, Dao-Cai; Xiang, Pu; Zhang, Jian-Nan; Sang, Ya-Xiong; Lin, Hong-Jun; Chen, Jie; Xie, Gang; Song, Hang; Zhao, Ying-Lan; Xie, Yong-Mei.
Afiliação
  • Wu TM; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.
  • Wang DC; Department of Pharmaceutical and Biological Engineering, College of Chemical Engineering, Sichuan University, Chengdu 610065, China.
  • Xiang P; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.
  • Zhang JN; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.
  • Sang YX; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.
  • Lin HJ; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.
  • Chen J; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.
  • Xie G; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.
  • Song H; Department of Pharmaceutical and Biological Engineering, College of Chemical Engineering, Sichuan University, Chengdu 610065, China.
  • Zhao YL; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China. Electronic address: zhaoyinglan@scu.edu.cn.
  • Xie YM; State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China. Electronic address: xieym@scu.edu.cn.
Bioorg Med Chem Lett ; 24(5): 1426-31, 2014 Mar 01.
Article em En | MEDLINE | ID: mdl-24491459
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonas / Benzamidas / Transdução de Sinais / Receptores Acoplados a Proteínas G Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonas / Benzamidas / Transdução de Sinais / Receptores Acoplados a Proteínas G Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China