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Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci.
Service, Susan K; Teslovich, Tanya M; Fuchsberger, Christian; Ramensky, Vasily; Yajnik, Pranav; Koboldt, Daniel C; Larson, David E; Zhang, Qunyuan; Lin, Ling; Welch, Ryan; Ding, Li; McLellan, Michael D; O'Laughlin, Michele; Fronick, Catrina; Fulton, Lucinda L; Magrini, Vincent; Swift, Amy; Elliott, Paul; Jarvelin, Marjo-Riitta; Kaakinen, Marika; McCarthy, Mark I; Peltonen, Leena; Pouta, Anneli; Bonnycastle, Lori L; Collins, Francis S; Narisu, Narisu; Stringham, Heather M; Tuomilehto, Jaakko; Ripatti, Samuli; Fulton, Robert S; Sabatti, Chiara; Wilson, Richard K; Boehnke, Michael; Freimer, Nelson B.
Afiliação
  • Service SK; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America.
  • Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Ramensky V; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America.
  • Yajnik P; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Koboldt DC; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Larson DE; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Zhang Q; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Lin L; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Welch R; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Ding L; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • McLellan MD; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • O'Laughlin M; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Fronick C; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Fulton LL; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Magrini V; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Swift A; Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
  • Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom ; Faculty of Medicine, St Mary's Campus, Imperial College London, London, United Kingdom.
  • Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom ; Institute of Health Sciences, University of Oulu, Oulu, Finland ; Biocenter Oulu, University of Oulu, Oulu, Finland ; Unit of Primary Ca
  • Kaakinen M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom ; Institute of Health Sciences, University of Oulu, Oulu, Finland ; Biocenter Oulu, University of Oulu, Oulu, Finland.
  • McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford, United Kingdom ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom ; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Headington, Ox
  • Peltonen L; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland ; The Program for Human and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
  • Pouta A; Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland ; Institute of Clinical Medicine/Obstetrics and Gynecology, University of Oulu, Oulu, Finland.
  • Bonnycastle LL; Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
  • Collins FS; Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
  • Narisu N; Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
  • Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Tuomilehto J; Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland.
  • Ripatti S; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland ; Hjelt Institute, University of Helsinki, Helsinki, Finland ; Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
  • Fulton RS; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Sabatti C; Department of Health and Research Policy, Stanford University, Stanford, California, United States of America.
  • Wilson RK; The Genome Institute at Washington University, St. Louis, Missouri, United States of America.
  • Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Freimer NB; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America.
PLoS Genet ; 10(1): e1004147, 2014 Jan.
Article em En | MEDLINE | ID: mdl-24497850
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Locos de Características Quantitativas / Estudo de Associação Genômica Ampla / HDL-Colesterol Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Locos de Características Quantitativas / Estudo de Associação Genômica Ampla / HDL-Colesterol Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos