4-(Methylnitrosamino)-1-(3-pyridyl) -1-butanone induces circulating microRNA deregulation in early lung carcinogenesis.

Wu, Jian Jun; Yang, Ti; Li, Xun; Xia, Yuan; Zhao, Yao; Zou, Fei; Jiang, Yi Guo

Wu, Jian Jun; Yang, Ti; Li, Xun; Xia, Yuan; Zhao, Yao; Zou, Fei; Jiang, Yi Guo.

Afiliação

Wu JJ; School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China; Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, Guangdong, China.
Yang T; Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, Guangdong, China.
Li X; Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, Guangdong, China.
Xia Y; School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, Guangdong, China.
Zhao Y; Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, Guangdong, China.
Zou F; School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China.
Jiang YG; School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, Guangdong, China; Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, Guangdong, China.

Biomed Environ Sci ; 27(1): 10-6, 2014 Jan.

Article em En | MEDLINE | ID: mdl-24553369

Assuntos

Adenocarcinoma/induzido quimicamente; Neoplasias Pulmonares/induzido quimicamente; MicroRNAs/metabolismo; Nitrosaminas/farmacologia; Animais; Carcinogênese; Linhagem Celular Tumoral; Regulação da Expressão Gênica/fisiologia; Humanos; Pulmão/efeitos dos fármacos; Pulmão/patologia; Neoplasias Pulmonares/sangue; Neoplasias Pulmonares/metabolismo; Masculino; MicroRNAs/sangue; MicroRNAs/genética; Ratos; Ratos Endogâmicos F344

Palavras-chave

Circulating microRNA; Early stage; Lung carcinogenesis; NNK

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenocarcinoma / MicroRNAs / Neoplasias Pulmonares / Nitrosaminas Limite: Animals / Humans / Male Idioma: En Revista: Biomed Environ Sci Assunto da revista: SAUDE AMBIENTAL Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China

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