Liposomes of phosphatidylcholine and cholesterol induce an M2-like macrophage phenotype reprogrammable to M1 pattern with the involvement of B-1 cells.

Cruz-Leal, Yoelys; Lucatelli Laurindo, María Fernanda; Osugui, Lika; Luzardo, María Del Carmen; López-Requena, Alejandro; Alonso, María Eugenia; Álvarez, Carlos; Popi, Ana Flavia; Mariano, Mario; Pérez, Rolando; Lanio, María Eliana

Cruz-Leal, Yoelys; Lucatelli Laurindo, María Fernanda; Osugui, Lika; Luzardo, María Del Carmen; López-Requena, Alejandro; Alonso, María Eugenia; Álvarez, Carlos; Popi, Ana Flavia; Mariano, Mario; Pérez, Rolando; Lanio, María Eliana.

Afiliação

Cruz-Leal Y; Center for Protein Studies, Faculty of Biology, University of Havana, Havana 10400, Cuba.
Lucatelli Laurindo MF; Immunology Discipline, Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo (UNIFESP) Paulista Medicine School, São Paulo 04023-062, São Paulo, Brazil.
Osugui L; Immunology Discipline, Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo (UNIFESP) Paulista Medicine School, São Paulo 04023-062, São Paulo, Brazil.
Luzardo Mdel C; Center for Protein Studies, Faculty of Biology, University of Havana, Havana 10400, Cuba.
López-Requena A; Research Division, Center of Molecular Immunology (CIM), Havana 11600, Cuba.
Alonso ME; Center for Protein Studies, Faculty of Biology, University of Havana, Havana 10400, Cuba.
Álvarez C; Center for Protein Studies, Faculty of Biology, University of Havana, Havana 10400, Cuba.
Popi AF; Immunology Discipline, Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo (UNIFESP) Paulista Medicine School, São Paulo 04023-062, São Paulo, Brazil.
Mariano M; Immunology Discipline, Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo (UNIFESP) Paulista Medicine School, São Paulo 04023-062, São Paulo, Brazil.
Pérez R; Research Division, Center of Molecular Immunology (CIM), Havana 11600, Cuba. Electronic address: rolando@cim.sld.cu.
Lanio ME; Center for Protein Studies, Faculty of Biology, University of Havana, Havana 10400, Cuba. Electronic address: mlanio@fbio.uh.cu.

Immunobiology ; 219(6): 403-15, 2014 Jun.

Article em En | MEDLINE | ID: mdl-24594322

Assuntos

Linfócitos B/imunologia; Colesterol/farmacologia; Lipossomos/farmacologia; Macrófagos Peritoneais/imunologia; Ovalbumina/farmacologia; 1,2-Dipalmitoilfosfatidilcolina/farmacologia; Transferência Adotiva; Animais; Arginase/biossíntese; Linfócitos B/transplante; Proliferação de Células/efeitos dos fármacos; Células Cultivadas; Portadores de Fármacos/farmacologia; Interferon gama/biossíntese; Interleucina-10/metabolismo; Interleucina-12/biossíntese; Interleucina-6/biossíntese; Lipopolissacarídeos/imunologia; Ativação de Macrófagos/imunologia; Macrófagos Peritoneais/citologia; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Óxido Nítrico/biossíntese; Fenótipo; Fosfatidilcolinas/farmacologia

Palavras-chave

B-1 cells; Liposomes; Macrophage polarization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Ovalbumina / Colesterol / Macrófagos Peritoneais / Lipossomos Limite: Animals Idioma: En Revista: Immunobiology Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Cuba

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