p53 haploinsufficiency and functional abnormalities in multiple myeloma.

Teoh, P J; Chung, T H; Sebastian, S; Choo, S N; Yan, J; Ng, S B; Fonseca, R; Chng, W J

Teoh, P J; Chung, T H; Sebastian, S; Choo, S N; Yan, J; Ng, S B; Fonseca, R; Chng, W J.

Afiliação

Teoh PJ; 1] Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore [2] Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Chung TH; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Sebastian S; Department of Hematology-Oncology, Mayo Clinic, Scottsdale, AZ, USA.
Choo SN; Department of Pathology, National University Cancer Institute of Singapore, National University Health System, Singapore.
Yan J; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Ng SB; 1] Department of Pathology, National University Cancer Institute of Singapore, National University Health System, Singapore [2] Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Fonseca R; Department of Hematology-Oncology, Mayo Clinic, Scottsdale, AZ, USA.
Chng WJ; 1] Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore [2] Cancer Science Institute of Singapore, National University of Singapore, Singapore [3] Department of Haematology-Oncology, National University Cancer Institute of Singapore, National Universit

Leukemia ; 28(10): 2066-74, 2014 Oct.

Article em En | MEDLINE | ID: mdl-24625551

Assuntos

Genes p53; Haploinsuficiência; Mieloma Múltiplo/genética; Mieloma Múltiplo/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Alelos; Apoptose; Linhagem Celular Tumoral; Proliferação de Células; Sobrevivência Celular; Cromossomos Humanos Par 17; Hibridização Genômica Comparativa; Metilação de DNA; Deleção de Genes; Inativação Gênica; Humanos; Prognóstico; Regiões Promotoras Genéticas; Transdução de Sinais; Resultado do Tratamento; Proteína Supressora de Tumor p53/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genes p53 / Proteína Supressora de Tumor p53 / Haploinsuficiência / Mieloma Múltiplo Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Singapura

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