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The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB.
Jiang, Rongrong; Li, Yuan; Zhang, Aihua; Wang, Bairu; Xu, Yuan; Xu, Wenchao; Zhao, Yue; Luo, Fei; Liu, Qizhan.
Afiliação
  • Jiang R; Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China; The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China.
  • Li Y; Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China; The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China.
  • Zhang A; Department of Toxicology, School of Public Health, Guiyang Medical University, Guiyang 550004, Guizhou, PR China.
  • Wang B; Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China; The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China.
  • Xu Y; Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China; The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China.
  • Xu W; Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China; The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China.
  • Zhao Y; Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China; The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China.
  • Luo F; Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China; The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China.
  • Liu Q; Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China; The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, PR China. Electronic address: drqzliu@hotmail
Toxicol Lett ; 227(2): 91-8, 2014 Jun 05.
Article em En | MEDLINE | ID: mdl-24704393
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Queratinócitos / NF-kappa B / Compostos de Sódio / Arsenitos / Proteínas ras / MicroRNAs / Epigênese Genética Limite: Animals / Humans Idioma: En Revista: Toxicol Lett Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Queratinócitos / NF-kappa B / Compostos de Sódio / Arsenitos / Proteínas ras / MicroRNAs / Epigênese Genética Limite: Animals / Humans Idioma: En Revista: Toxicol Lett Ano de publicação: 2014 Tipo de documento: Article