Promiscuity is not always bad.

Ru, Heng; Zhang, Pengfei; Wu, Hao

Ru, Heng; Zhang, Pengfei; Wu, Hao.

Afiliação

Ru H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
Zhang P; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
Wu H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA. Electronic address: hao.wu@childrens.harvard.edu.

Mol Cell ; 54(2): 208-9, 2014 Apr 24.

Article em En | MEDLINE | ID: mdl-24766883

RESUMO

In the recent issue of Cell, Bonham et al. (2014) reveal that the sorting adaptor TIRAP regulates the assembly of the Myddosome upon Toll-like receptor activation from both the cell surface and endosomes through its promiscuous binding to lipids.

Assuntos

Imunidade Inata; Glicoproteínas de Membrana/metabolismo; Receptores de Interleucina-1/metabolismo; Transdução de Sinais; Receptores Toll-Like/metabolismo; Animais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Transdução de Sinais / Receptores de Interleucina-1 / Receptores Toll-Like / Imunidade Inata Limite: Animals Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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