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Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation.
Rivlin, Noa; Katz, Shir; Doody, Maayan; Sheffer, Michal; Horesh, Stav; Molchadsky, Alina; Koifman, Gabriela; Shetzer, Yoav; Goldfinger, Naomi; Rotter, Varda; Geiger, Tamar.
Afiliação
  • Rivlin N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and.
  • Katz S; Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
  • Doody M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and.
  • Sheffer M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and.
  • Horesh S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and.
  • Molchadsky A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and.
  • Koifman G; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and.
  • Shetzer Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and.
  • Goldfinger N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and.
  • Rotter V; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; and varda.rotter@weizmann.ac.il geiger@post.tau.ac.il.
  • Geiger T; Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel varda.rotter@weizmann.ac.il geiger@post.tau.ac.il.
Proc Natl Acad Sci U S A ; 111(19): 7006-11, 2014 May 13.
Article em En | MEDLINE | ID: mdl-24778235
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Proteína Supressora de Tumor p53 / Síndrome de Li-Fraumeni / Células-Tronco Embrionárias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Proteína Supressora de Tumor p53 / Síndrome de Li-Fraumeni / Células-Tronco Embrionárias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article