Your browser doesn't support javascript.
loading
Breakthrough invasive Candida glabrata in patients on micafungin: a novel FKS gene conversion correlated with sequential elevation of MIC.
Saraya, Takeshi; Tanabe, Koichi; Araki, Koji; Yonetani, Shota; Makino, Hiroshi; Watanabe, Takayasu; Tsujimoto, Naoki; Takata, Saori; Kurai, Daisuke; Ishii, Haruyuki; Miyazaki, Yoshitsugu; Takizawa, Hajime; Goto, Hajime.
Afiliação
  • Saraya T; Kyorin University School of Medicine, Department of Respiratory Medicine, Mitaka, Tokyo, Japan sara@yd5.so-net.ne.jp.
  • Tanabe K; Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Tokyo, Japan.
  • Araki K; Kyorin University School of Medicine, Department of Laboratory Medicine, Mitaka, Tokyo, Japan.
  • Yonetani S; Kyorin University School of Medicine, Department of Laboratory Medicine, Mitaka, Tokyo, Japan.
  • Makino H; Kyorin University School of Medicine, Department of Laboratory Medicine, Mitaka, Tokyo, Japan.
  • Watanabe T; Kyorin University School of Medicine, Department of Respiratory Medicine, Mitaka, Tokyo, Japan.
  • Tsujimoto N; Kyorin University School of Medicine, Department of Respiratory Medicine, Mitaka, Tokyo, Japan.
  • Takata S; Kyorin University School of Medicine, Department of Respiratory Medicine, Mitaka, Tokyo, Japan.
  • Kurai D; Kyorin University School of Medicine, Department of Respiratory Medicine, Mitaka, Tokyo, Japan.
  • Ishii H; Kyorin University School of Medicine, Department of Respiratory Medicine, Mitaka, Tokyo, Japan.
  • Miyazaki Y; Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Tokyo, Japan.
  • Takizawa H; Kyorin University School of Medicine, Department of Respiratory Medicine, Mitaka, Tokyo, Japan.
  • Goto H; Kyorin University School of Medicine, Department of Respiratory Medicine, Mitaka, Tokyo, Japan.
J Clin Microbiol ; 52(7): 2709-12, 2014 Jul.
Article em En | MEDLINE | ID: mdl-24789192
ABSTRACT
Candida glabrata strains sequentially isolated from blood developed resistance to micafungin (MICs from <0.015 to 4 µg/ml). A novel mutation identified in micafungin-resistant strains at bp 262 of FKS2 (containing a deletion of F659 [F659del]) was inserted into the homologous region in FKS1.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Fúngicas / Candida glabrata / Equinocandinas / Lipopeptídeos / Candidemia / Conversão Gênica / Antifúngicos Tipo de estudo: Prognostic_studies Limite: Aged80 / Humans / Male Idioma: En Revista: J Clin Microbiol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Fúngicas / Candida glabrata / Equinocandinas / Lipopeptídeos / Candidemia / Conversão Gênica / Antifúngicos Tipo de estudo: Prognostic_studies Limite: Aged80 / Humans / Male Idioma: En Revista: J Clin Microbiol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Japão