Hb Fontainebleau (HBA2: c.64G > C) in the United Arab Emirates.
Hemoglobin
; 38(3): 216-20, 2014.
Article
em En
| MEDLINE
| ID: mdl-24826794
ABSTRACT
Hb Fontainebleau (HBA2 c.64G > C) is a rare α-globin variant, which has previously been described in only 10 individuals worldwide. We report here 12 additional cases identified in our laboratory. These included the first case of a homozygosity for Hb Fontainebleau and cases in which Hb Fontainebleau occurred in combination with deletional and nondeletional α-thalassemia (α-thal). The prevalence of Hb Fontainebleau in the samples submitted to our laboratory for premarital hemoglobinopathy screening was 0.24%, the highest reported prevalence to date, indicating that this is a comparatively common variant in the United Arab Emirates (UAE).
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemoglobinas Anormais
/
Talassemia alfa
/
Homozigoto
Tipo de estudo:
Prevalence_studies
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Hemoglobin
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Emirados Árabes Unidos