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Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival.
Zhu, Zhe; Khan, Muhammad Amir; Weiler, Markus; Blaes, Jonas; Jestaedt, Leonie; Geibert, Madeleine; Zou, Peng; Gronych, Jan; Bernhardt, Olga; Korshunov, Andrey; Bugner, Verena; Lichter, Peter; Radlwimmer, Bernhard; Heiland, Sabine; Bendszus, Martin; Wick, Wolfgang; Liu, Hai-Kun.
Afiliação
  • Zhu Z; Helmholtz Young Investigator Group, Normal and Neoplastic CNS Stem Cells, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Khan MA; Helmholtz Young Investigator Group, Normal and Neoplastic CNS Stem Cells, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Weiler M; Clinical Cooperation Unit Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Department of Neurooncology, University Clinic Heidelberg and German Cancer Consortium (DKTK), Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
  • Blaes J; Clinical Cooperation Unit Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Jestaedt L; Department of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
  • Geibert M; Helmholtz Young Investigator Group, Normal and Neoplastic CNS Stem Cells, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Zou P; Helmholtz Young Investigator Group, Normal and Neoplastic CNS Stem Cells, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Gronych J; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Bernhardt O; Helmholtz Young Investigator Group, Normal and Neoplastic CNS Stem Cells, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Korshunov A; Department of Neuropathology, Heidelberg University Hospital, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany.
  • Bugner V; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Lichter P; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Radlwimmer B; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Heiland S; Department of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
  • Bendszus M; Department of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
  • Wick W; Clinical Cooperation Unit Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Department of Neurooncology, University Clinic Heidelberg and German Cancer Consortium (DKTK), Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
  • Liu HK; Helmholtz Young Investigator Group, Normal and Neoplastic CNS Stem Cells, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address: l.haikun@dkfz-heidelberg.de.
Cell Stem Cell ; 15(2): 185-98, 2014 Aug 07.
Article em En | MEDLINE | ID: mdl-24835569
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Encefálicas / Glioma Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Encefálicas / Glioma Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Alemanha