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TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells.
Steinke, Farrah C; Yu, Shuyang; Zhou, Xinyuan; He, Bing; Yang, Wenjing; Zhou, Bo; Kawamoto, Hiroshi; Zhu, Jun; Tan, Kai; Xue, Hai-Hui.
Afiliação
  • Steinke FC; Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242.
  • Yu S; Interdisciplinary Immunology Graduate Program, Carver College of Medicine, University of Iowa, Iowa City, IA 52242.
  • Zhou X; State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, P. R. China 100193.
  • He B; Insitute of Immunology, Third Military Medical University, Chongqing, P. R. China 400038.
  • Yang W; Interdisciplinary Graduate Program in Genetics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242.
  • Zhou B; Development Biology Center, NHLBI, NIH, Bethesda, MD 20892.
  • Kawamoto H; Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242.
  • Zhu J; Department of Immunology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan 606-8507.
  • Tan K; Development Biology Center, NHLBI, NIH, Bethesda, MD 20892.
  • Xue HH; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242.
Nat Immunol ; 15(7): 646-656, 2014 Jul.
Article em En | MEDLINE | ID: mdl-24836425
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Linfócitos T CD4-Positivos / Antígenos CD4 / Linfócitos T CD8-Positivos / Fator 1 de Ligação ao Facilitador Linfoide / Fator 1 de Transcrição de Linfócitos T / Subunidade alfa 3 de Fator de Ligação ao Core Limite: Animals Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Linfócitos T CD4-Positivos / Antígenos CD4 / Linfócitos T CD8-Positivos / Fator 1 de Ligação ao Facilitador Linfoide / Fator 1 de Transcrição de Linfócitos T / Subunidade alfa 3 de Fator de Ligação ao Core Limite: Animals Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2014 Tipo de documento: Article