GenomeVISTA--an integrated software package for whole-genome alignment and visualization.
Bioinformatics
; 30(18): 2654-5, 2014 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-24860159
ABSTRACT
UNLABELLED With the ubiquitous generation of complete genome assemblies for a variety of species, efficient tools for whole-genome alignment along with user-friendly visualization are critically important. Our VISTA family of tools for comparative genomics, based on algorithms for pairwise and multiple alignments of genomic sequences and whole-genome assemblies, has become one of the standard techniques for comparative analysis. Most of the VISTA programs have been implemented as Web-accessible servers and are extensively used by the biomedical community. In this manuscript, we introduce GenomeVISTA a novel implementation that incorporates most features of the VISTA family--fast and accurate alignment, visualization capabilities, GUI and analytical tools within a stand-alone software package. GenomeVISTA thus provides flexibility and security for users who need to conduct whole-genome comparisons on their own computers. AVAILABILITY AND IMPLEMENTATION Implemented in Perl, C/C++ and Java, the source code is freely available for download at the VISTA Web site http//genome.lbl.gov/vista/.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Alinhamento de Sequência
/
Genômica
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2014
Tipo de documento:
Article