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APOL1 risk variants enhance podocyte necrosis through compromising lysosomal membrane permeability.
Lan, Xiqian; Jhaveri, Aakash; Cheng, Kang; Wen, Hongxiu; Saleem, Moin A; Mathieson, Peter W; Mikulak, Joanna; Aviram, Sharon; Malhotra, Ashwani; Skorecki, Karl; Singhal, Pravin C.
Afiliação
  • Lan X; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra-North Shore Long Island Jewish School of Medicine School, Hempstead, New York;
  • Jhaveri A; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra-North Shore Long Island Jewish School of Medicine School, Hempstead, New York;
  • Cheng K; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra-North Shore Long Island Jewish School of Medicine School, Hempstead, New York;
  • Wen H; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra-North Shore Long Island Jewish School of Medicine School, Hempstead, New York;
  • Saleem MA; Renal Academic Unit, University of Bristol, Bristol, United Kingdom;
  • Mathieson PW; Renal Academic Unit, University of Bristol, Bristol, United Kingdom;
  • Mikulak J; Laboratory of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy; and.
  • Aviram S; Nephrology and Molecular Medicine, Technion Institute of Technology and Rambam Medical Center, Haifa, Israel.
  • Malhotra A; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra-North Shore Long Island Jewish School of Medicine School, Hempstead, New York;
  • Skorecki K; Nephrology and Molecular Medicine, Technion Institute of Technology and Rambam Medical Center, Haifa, Israel.
  • Singhal PC; Renal Molecular Research Laboratory, Feinstein Institute for Medical Research, Hofstra-North Shore Long Island Jewish School of Medicine School, Hempstead, New York; psinghal@nshs.edu.
Am J Physiol Renal Physiol ; 307(3): F326-36, 2014 Aug 01.
Article em En | MEDLINE | ID: mdl-24899058
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteínas / Variação Genética / Podócitos / Lipoproteínas HDL / Lisossomos Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Am J Physiol Renal Physiol Assunto da revista: FISIOLOGIA / NEFROLOGIA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteínas / Variação Genética / Podócitos / Lipoproteínas HDL / Lisossomos Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Am J Physiol Renal Physiol Assunto da revista: FISIOLOGIA / NEFROLOGIA Ano de publicação: 2014 Tipo de documento: Article