Automated Lead Optimization of MMP-12 Inhibitors Using a Genetic Algorithm.

Pickett, Stephen D; Green, Darren V S; Hunt, David L; Pardoe, David A; Hughes, Ian

Pickett, Stephen D; Green, Darren V S; Hunt, David L; Pardoe, David A; Hughes, Ian.

Afiliação

Pickett SD; GlaxoSmithKline Research and Development, Stevenage, Herts, SG1 2NY, United Kingdom.
Green DV; GlaxoSmithKline Research and Development, Stevenage, Herts, SG1 2NY, United Kingdom.
Hunt DL; Tessella plc, Stevenage, Herts, SG1 2EF, United Kingdom.
Pardoe DA; GlaxoSmithKline Research and Development, Harlow, Essex, CM19 5AW, United Kingdom.
Hughes I; GlaxoSmithKline Research and Development, Harlow, Essex, CM19 5AW, United Kingdom.

ACS Med Chem Lett ; 2(1): 28-33, 2011 Jan 13.

Article em En | MEDLINE | ID: mdl-24900251

Palavras-chave

Lead optimization; MMP-12 inhibitors; genetic algorithm; microfluidic chemistry

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Reino Unido

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