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Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes.
Li, Aiwen; Yuan, Chester C; Chow, David; Chen, Michelle; Emery, Maurice G; Hale, Clarence; Zhang, Xiping; Subramanian, Raju; St Jean, David J; Komorowski, Renee; Véniant, Murielle; Wang, Minghan; Fotsch, Christopher.
Afiliação
  • Li A; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Yuan CC; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Chow D; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Chen M; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Emery MG; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Hale C; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Zhang X; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Subramanian R; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • St Jean DJ; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Komorowski R; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Véniant M; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Wang M; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
  • Fotsch C; Departments of Chemistry Research and Discovery, Metabolic Disorders, and Pharmacokinetics and Drug Metabolism, Amgen Inc. , One Amgen Center Drive, Thousand Oaks, California 91320, United States.
ACS Med Chem Lett ; 2(11): 824-7, 2011 Nov 10.
Article em En | MEDLINE | ID: mdl-24900270
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Estados Unidos