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Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists.
Piotrowski, David W; Futatsugi, Kentaro; Warmus, Joseph S; Orr, Suvi T M; Freeman-Cook, Kevin D; Londregan, Allyn T; Wei, Liuqing; Jennings, Sandra M; Herr, Michael; Coffey, Steven B; Jiao, Wenhua; Storer, Gregory; Hepworth, David; Wang, Jian; Lavergne, Sophie Y; Chin, Janice E; Hadcock, John R; Brenner, Martin B; Wolford, Angela C; Janssen, Ann M; Roush, Nicole S; Buxton, Joanne; Hinchey, Terri; Kalgutkar, Amit S; Sharma, Raman; Flynn, Declan A.
Afiliação
  • Piotrowski DW; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Futatsugi K; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Warmus JS; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Orr ST; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Freeman-Cook KD; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Londregan AT; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Wei L; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Jennings SM; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Herr M; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Coffey SB; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Jiao W; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Storer G; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Hepworth D; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Wang J; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Lavergne SY; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Chin JE; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Hadcock JR; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Brenner MB; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Wolford AC; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Janssen AM; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Roush NS; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Buxton J; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Hinchey T; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Kalgutkar AS; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Sharma R; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
  • Flynn DA; Pfizer Worldwide Research and Development , Groton, Connecticut 06340, United States.
ACS Med Chem Lett ; 4(1): 63-8, 2013 Jan 10.
Article em En | MEDLINE | ID: mdl-24900564
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Estados Unidos