Broadening the scope of Baeyer-Villiger monooxygenase activities toward α,ß-unsaturated ketones: a promising route to chiral enol-lactones and ene-lactones.
Chem Commun (Camb)
; 50(58): 7793-6, 2014 Jul 25.
Article
em En
| MEDLINE
| ID: mdl-24903773
ABSTRACT
Three regiodivergent Baeyer-Villiger mono-oxygenases (enantioselectively) oxidized a series of cyclic α,ß-unsaturated ketones into (chiral) either enol-lactones or ene-lactones. An easy-to-use and efficient biocatalytic process based on a host-microorganism deprived of unwanted activities (knock-out mutant) was developed to enable the exclusive synthesis of unsaturated lactones.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxigenases
/
Cetonas
/
Lactonas
Idioma:
En
Revista:
Chem Commun (Camb)
Assunto da revista:
QUIMICA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
França