Protective effect of Dl-3n-butylphthalide on learning and memory impairment induced by chronic intermittent hypoxia-hypercapnia exposure.

Min, Jing-jing; Huo, Xin-long; Xiang, Ling-yun; Qin, Yan-qing; Chai, Ke-qin; Wu, Bin; Jin, Lu; Wang, Xiao-tong

Min, Jing-jing; Huo, Xin-long; Xiang, Ling-yun; Qin, Yan-qing; Chai, Ke-qin; Wu, Bin; Jin, Lu; Wang, Xiao-tong.

Afiliação

Min JJ; 1] The Center of Neurology and Rehabilitation, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China [2] The First People's Hospital of Huzhou, Huzhou 313000, China [3].
Huo XL; 1] The Center of Neurology and Rehabilitation, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China [2].
Xiang LY; The Center of Neurology and Rehabilitation, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Qin YQ; The Center of Neurology and Rehabilitation, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Chai KQ; The Center of Neurology and Rehabilitation, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Wu B; Wenzhou Medical University, Wenzhou 325027, China.
Jin L; The Center of Neurology and Rehabilitation, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Wang XT; The Center of Neurology and Rehabilitation, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China.

Sci Rep ; 4: 5555, 2014 Jul 03.

Article em En | MEDLINE | ID: mdl-24990154

Assuntos

Benzofuranos/farmacologia; Hipercapnia/tratamento farmacológico; Hipóxia Encefálica/tratamento farmacológico; Aprendizagem em Labirinto/efeitos dos fármacos; Fármacos Neuroprotetores/farmacologia; Animais; Apoptose; Benzofuranos/uso terapêutico; Fator Neurotrófico Derivado do Encéfalo/metabolismo; Avaliação Pré-Clínica de Medicamentos; Hipercapnia/etiologia; Hipercapnia/psicologia; Hipóxia Encefálica/etiologia; Hipóxia Encefálica/psicologia; Masculino; Memória/efeitos dos fármacos; Renovação Mitocondrial; Fármacos Neuroprotetores/uso terapêutico; Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo; Doença Pulmonar Obstrutiva Crônica/complicações; Ratos; Ratos Sprague-Dawley; Sirtuína 1/metabolismo; Fatores de Transcrição/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzofuranos / Hipóxia Encefálica / Fármacos Neuroprotetores / Aprendizagem em Labirinto / Hipercapnia Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2014 Tipo de documento: Article

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