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Determinants of bisphenol A and phthalate metabolites in urine of Flemish adolescents.
Geens, Tinne; Bruckers, Liesbeth; Covaci, Adrian; Schoeters, Greet; Fierens, Tine; Sioen, Isabelle; Vanermen, Guido; Baeyens, Willy; Morrens, Bert; Loots, Ilse; Nelen, Vera; de Bellevaux, Benoit Nemery; Larebeke, Nik Van; Hond, Elly Den.
Afiliação
  • Geens T; Toxicological Center, University of Antwerp, Belgium.
  • Bruckers L; Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Belgium.
  • Covaci A; Toxicological Center, University of Antwerp, Belgium. Electronic address: adrian.covaci@uantwerpen.be.
  • Schoeters G; Environmental Risk and Health Unit, Flemish Institute for Technological Research (VITO), Belgium; Department of Biomedical Sciences, University of Antwerp, Belgium.
  • Fierens T; Environmental Risk and Health Unit, Flemish Institute for Technological Research (VITO), Belgium; Department of Public Health, Ghent University, Belgium.
  • Sioen I; Department of Public Health, Ghent University, Belgium.
  • Vanermen G; Environmental Analysis and Technology Unit, Flemish Institute for Technological Research (VITO), Belgium.
  • Baeyens W; Department of Analytical and Environmental Chemistry, Vrije Universiteit Brussel (VUB), Belgium.
  • Morrens B; Department of Sociology, University of Antwerp, Belgium.
  • Loots I; Department of Sociology, University of Antwerp, Belgium.
  • Nelen V; Provincial Institute for Hygiene, Antwerp, Belgium.
  • de Bellevaux BN; Department of Public Health, Occupational and Environmental Medicine, University of Leuven, Belgium.
  • Larebeke NV; Department of Analytical and Environmental Chemistry, Vrije Universiteit Brussel (VUB), Belgium and (retired) Study Centre for Carcinogenesis and Primary Prevention of Cancer, Ghent University, Belgium.
  • Hond ED; Environmental Risk and Health Unit, Flemish Institute for Technological Research (VITO), Belgium.
Environ Res ; 134: 110-7, 2014 Oct.
Article em En | MEDLINE | ID: mdl-25127521
As part of the second Flemish Environment and Health Study (FLEHS II), bisphenol-A (BPA) and different phthalate metabolites were analyzed, for the first time, in the urine of 210 adolescents in Flanders, Belgium. All chemicals had a detection frequency above 90%. For all compounds, except the sum of DEHP, highest levels were detected during spring. Average values for the Flemish adolescents were in an agreement with concentrations found in different international studies, all confirming the ubiquity of BPA and phthalate exposure. There was a significant correlation between BPA and the different phthalate metabolites (r between 0.26 and 0.39; p<0.01). Shared sources of exposure to BPA and phthalates, such as food packaging, were suggested to be responsible for this positive correlation. Different determinants of exposure were evaluated in relation to the urinary concentrations of these chemicals. For BPA, a significant association was observed with household income class, smoking and exposure to environmental tobacco smoke. For phthalates, the following significant associations were observed: age (MBzP), educational level of the adolescent (MBzP), equivalent household income (MnBP), use of personal care products (MnBP and MBzP), wall paper in house (MnBP and MBzP) and use of local vegetables (MnBP and MBzP).
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Ácidos Ftálicos / Poluentes Químicos da Água / Compostos Benzidrílicos Limite: Adolescent / Humans País/Região como assunto: Europa Idioma: En Revista: Environ Res Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Bélgica

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Ácidos Ftálicos / Poluentes Químicos da Água / Compostos Benzidrílicos Limite: Adolescent / Humans País/Região como assunto: Europa Idioma: En Revista: Environ Res Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Bélgica