Treatment of camptocormia with continuous subcutaneous infusions of apomorphine: 1-year prospective pilot study.
J Neural Transm (Vienna)
; 122(6): 835-9, 2015 Jun.
Article
em En
| MEDLINE
| ID: mdl-25134820
ABSTRACT
Camptocormia is defined as a marked dystonic flexion of the trunk in the sagittal plane. Camptocormia responds poorly to botulinum toxin injections, manipulation with dopaminergic treatment, and deep brain stimulation. We designed a prospective pilot study to assess the effect of apomorphine infusions on camptocormia. Five patients were enrolled. All five patients responded well to this treatment. The fact that camptocormia responds so well to apomorphine may be explained by the sustained stimulation of the ventrolateral striatal D1 receptors, alleviating this type of dystonia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Curvaturas da Coluna Vertebral
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Atrofia Muscular Espinal
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Apomorfina
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Agonistas de Dopamina
Tipo de estudo:
Observational_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Neural Transm (Vienna)
Ano de publicação:
2015
Tipo de documento:
Article