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JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation.
Besancenot, Rodolphe; Roos-Weil, Damien; Tonetti, Carole; Abdelouahab, Hadjer; Lacout, Catherine; Pasquier, Florence; Willekens, Christophe; Rameau, Philippe; Lecluse, Yann; Micol, Jean-Baptiste; Constantinescu, Stefan N; Vainchenker, William; Solary, Eric; Giraudier, Stéphane.
Afiliação
  • Besancenot R; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Université Paris Diderot, Paris, France;
  • Roos-Weil D; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Université Paris Diderot, Paris, France;
  • Tonetti C; Assistance Publique-Hôpitaux de Paris, Hématologie Biologique, Hôpital Henri-Mondor, Créteil, France; Faculty of Medicine, University Paris-12, Créteil, France;
  • Abdelouahab H; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Université Paris Diderot, Paris, France;
  • Lacout C; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Faculty of Medicine, University Paris-Sud 11, Le Kremlin-Bicêtre, France;
  • Pasquier F; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Université Paris Diderot, Paris, France;
  • Willekens C; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Université Paris Diderot, Paris, France;
  • Rameau P; Institut Gustave Roussy, Villejuif, France;
  • Lecluse Y; Institut Gustave Roussy, Villejuif, France;
  • Micol JB; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Faculty of Medicine, University Paris-Sud 11, Le Kremlin-Bicêtre, France;
  • Constantinescu SN; Ludwig Institute for Cancer Research and de Duve Institute, Brussels, Belgium; and Université Catholique de Louvain, Brussels, Belgium.
  • Vainchenker W; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Faculty of Medicine, University Paris-Sud 11, Le Kremlin-Bicêtre, France;
  • Solary E; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Faculty of Medicine, University Paris-Sud 11, Le Kremlin-Bicêtre, France;
  • Giraudier S; INSERM Unité Mixte de Recherche 1009, Villejuif, France; Integrated Research Cancer Institute in Villejuif, Villejuif, France; Assistance Publique-Hôpitaux de Paris, Hématologie Biologique, Hôpital Henri-Mondor, Créteil, France; Faculty of Medicine, University Paris-12, Créteil, France;
Blood ; 124(13): 2104-15, 2014 Sep 25.
Article em En | MEDLINE | ID: mdl-25143485
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoantígenos / Megacariócitos / Diferenciação Celular / Proteínas de Ligação ao Ferro / Janus Quinase 2 / Receptores de Trombopoetina / Iodeto Peroxidase Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoantígenos / Megacariócitos / Diferenciação Celular / Proteínas de Ligação ao Ferro / Janus Quinase 2 / Receptores de Trombopoetina / Iodeto Peroxidase Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2014 Tipo de documento: Article