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Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis.
Risbridger, Gail P; Taylor, Renea A; Clouston, David; Sliwinski, Ania; Thorne, Heather; Hunter, Sally; Li, Jason; Mitchell, Gillian; Murphy, Declan; Frydenberg, Mark; Pook, David; Pedersen, John; Toivanen, Roxanne; Wang, Hong; Papargiris, Melissa; Lawrence, Mitchell G; Bolton, Damien M.
Afiliação
  • Risbridger GP; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.
  • Taylor RA; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia; Department of Physiology, Monash University, Melbourne, Victoria, Australia.
  • Clouston D; Tissupath, Mt. Waverley, Victoria, Australia.
  • Sliwinski A; kConFab, Research Department, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Familial Cancer Centre, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Division of Cancer Surgery, Peter MacCallum Cancer Centre, U
  • Thorne H; kConFab, Research Department, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Familial Cancer Centre, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Department of Oncology, Peter MacCallum Cancer Centre, Unive
  • Hunter S; Department of Oncology, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia.
  • Li J; Department of Oncology, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Bioinformatics, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia.
  • Mitchell G; kConFab, Research Department, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Familial Cancer Centre, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Department of Oncology, Peter MacCallum Cancer Centre, Unive
  • Murphy D; Division of Cancer Surgery, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Victoria, Australia; Epworth Research Centre, Epworth Healthcare, Victoria, Australia.
  • Frydenberg M; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia; Department of Urology, Monash Medical Centre, Monash University, Melbourne, Victoria, Australia.
  • Pook D; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.
  • Pedersen J; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia; Tissupath, Mt. Waverley, Victoria, Australia.
  • Toivanen R; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.
  • Wang H; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.
  • Papargiris M; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.
  • Lawrence MG; Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.
  • Bolton DM; Department of Urology, University of Melbourne, Austin Hospital, Melbourne Heidelberg, Victoria, Australia. Electronic address: damienmb@unimelb.edu.au.
Eur Urol ; 67(3): 496-503, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25154392
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Carcinoma Intraductal não Infiltrante / Proteína BRCA2 / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Animals / Humans / Male / Middle aged Idioma: En Revista: Eur Urol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Carcinoma Intraductal não Infiltrante / Proteína BRCA2 / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Animals / Humans / Male / Middle aged Idioma: En Revista: Eur Urol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália