Effect of yiqibushenhuoxue decoction on chronic obstructive pulmonary disease measured by St. George's respiratory disease questionnaire scores and forced expiratory volume.
J Tradit Chin Med
; 34(4): 445-9, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-25185362
ABSTRACT
OBJECTIVE:
To investigate the effects of Yiqibushenhuoxue decoction on stable chronic obstructive pulmonary disease (COPD) by observing its influences on patients' quality of life and airway inflammation.METHODS:
Seventy patients with stable COPD were randomly divided into a treatment group (n = 35) treated with Yiqibushenhuoxue decoction plus Seretide and a control group (n = 35) treated with Seretide only. The dosage of Yiqibushenhuoxue decoction was 100 mL each time, twice a day, and the dosage of Seretide was salmeterol 50 microg/fluticasone 250 microg twice a day. Both groups were treated for 12 weeks. Before and after the treatment, St George's respiratory disease questionnaire (SGRQ) scores, forced expiratory volume, and forced expiratory volume in 1 second/forced vital capacity (FEV1/ FVC) were measured.RESULTS:
The SGRQ scores in both groups were significantly lower than those before treatment (P < 0.05). After treatment, the total SGRQ scores and each subscore in the treatment group were significantly lower than those in the control group (P < 0.05). The percentage of the predicted FEV1% and FEV1/FVC were higher in both groups, but no statistical differences were detected from before to after the treatment or between the two groups (P > 0.05).CONCLUSION:
Yiqibushenhuoxue decoction could significantly decrease the SGRQ scores in patients with stable COPD, which suggests that it is able to improve patient symptoms.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Medicamentos de Ervas Chinesas
/
Volume Expiratório Forçado
/
Doença Pulmonar Obstrutiva Crônica
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Tradit Chin Med
Ano de publicação:
2014
Tipo de documento:
Article