Increased concanavalin A-induced suppressor cell activity in humans with occupational lead exposure.
Environ Res
; 48(1): 1-6, 1989 Feb.
Article
em En
| MEDLINE
| ID: mdl-2521599
ABSTRACT
E-rosette-forming cells (E-RFC), mitogen-induced blast transformation, OKT4+, OKT8+ cells, and their ratio were found to be normal in 10 subjects chronically exposed to lead with blood levels of 40-51 micrograms%. However, concanavalin A (Con A)-induced suppressor cell activity (SCA) in these subjects was significantly greater than in normal matched controls. The clinical relevance of this observation is not clear, but it may have some bearing on the various immunologic defects described in lead exposure.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos T Reguladores
/
Concanavalina A
/
Intoxicação por Chumbo
Limite:
Adult
/
Aged
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Environ Res
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Israel