Modification of ASC1 by UFM1 is crucial for ER&#945; transactivation and breast cancer development.

Yoo, Hee Min; Kang, Sung Hwan; Kim, Jae Yeon; Lee, Joo Eun; Seong, Min Woo; Lee, Seong Won; Ka, Seung Hyeun; Sou, Yu-Shin; Komatsu, Masaaki; Tanaka, Keiji; Lee, Soon Tae; Noh, Dong Young; Baek, Sung Hee; Jeon, Young Joo; Chung, Chin Ha

Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development.

Yoo, Hee Min; Kang, Sung Hwan; Kim, Jae Yeon; Lee, Joo Eun; Seong, Min Woo; Lee, Seong Won; Ka, Seung Hyeun; Sou, Yu-Shin; Komatsu, Masaaki; Tanaka, Keiji; Lee, Soon Tae; Noh, Dong Young; Baek, Sung Hee; Jeon, Young Joo; Chung, Chin Ha.

Afiliação

Yoo HM; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.
Kang SH; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.
Kim JY; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.
Lee JE; Departments of Internal Medicine, Surgery, and Neurology, College of Medicine, Seoul National University, Seoul 110-744, Korea.
Seong MW; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.
Lee SW; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.
Ka SH; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.
Sou YS; Laboratory of Frontier Science, Tokyo Metropolitan Institute of Medical Science, Tokyo 113-8613, Japan.
Komatsu M; Laboratory of Frontier Science, Tokyo Metropolitan Institute of Medical Science, Tokyo 113-8613, Japan.
Tanaka K; Laboratory of Frontier Science, Tokyo Metropolitan Institute of Medical Science, Tokyo 113-8613, Japan.
Lee ST; Departments of Internal Medicine, Surgery, and Neurology, College of Medicine, Seoul National University, Seoul 110-744, Korea.
Noh DY; Departments of Internal Medicine, Surgery, and Neurology, College of Medicine, Seoul National University, Seoul 110-744, Korea.
Baek SH; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea.
Jeon YJ; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea. Electronic address: gydbs98@snu.ac.kr.
Chung CH; School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea. Electronic address: chchung@snu.ac.kr.

Mol Cell ; 56(2): 261-274, 2014 Oct 23.

Article em En | MEDLINE | ID: mdl-25219498

Assuntos

Sistema y+ de Transporte de Aminoácidos/metabolismo; Neoplasias da Mama/patologia; Receptor alfa de Estrogênio/metabolismo; Proteínas/química; Sistema y+ de Transporte de Aminoácidos/química; Sistema y+ de Transporte de Aminoácidos/genética; Animais; Neoplasias da Mama/metabolismo; Proteínas de Transporte/metabolismo; Linhagem Celular Tumoral; Cisteína Endopeptidases/metabolismo; Proteína p300 Associada a E1A/genética; Ativação Enzimática/genética; Estradiol/genética; Estradiol/metabolismo; Antagonistas de Estrogênios/farmacologia; Receptor alfa de Estrogênio/genética; Feminino; Células HEK293; Humanos; Células MCF-7; Camundongos; Camundongos Nus; Coativador 1 de Receptor Nuclear/genética; Regiões Promotoras Genéticas/genética; Ligação Proteica/genética; Proteínas/metabolismo; Tamoxifeno/farmacologia; Ativação Transcricional; Ubiquitina/metabolismo; Enzimas Ativadoras de Ubiquitina/genética; Ubiquitina-Proteína Ligases/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas / Sistema y/ de Transporte de Aminoácidos / Receptor alfa de Estrogênio Limite: Animals / Female / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google