Impaired degradation and aberrant phagocytosis of necrotic cell debris in the peripheral blood of patients with primary Sjögren's syndrome.

Fragoulis, George E; Vakrakou, Aigli G; Papadopoulou, Anna; Germenis, Anastasios; Kanavakis, Emmanouel; Moutsopoulos, Haralampos M; Manoussakis, Menelaos N

Fragoulis, George E; Vakrakou, Aigli G; Papadopoulou, Anna; Germenis, Anastasios; Kanavakis, Emmanouel; Moutsopoulos, Haralampos M; Manoussakis, Menelaos N.

Afiliação

Fragoulis GE; Department of Pathophysiology, School of Medicine, National and Kapodestrian University of Athens, Greece.
Vakrakou AG; Department of Pathophysiology, School of Medicine, National and Kapodestrian University of Athens, Greece.
Papadopoulou A; Department of Medical Genetics, National and Kapodestrian University of Athens, Choremio Research Laboratory, "Aghia Sophia" Children's Hospital, Athens, Greece.
Germenis A; Department of Immunology and Histocompatibility, Medical School, University of Thessaly, Greece.
Kanavakis E; Department of Medical Genetics, National and Kapodestrian University of Athens, Choremio Research Laboratory, "Aghia Sophia" Children's Hospital, Athens, Greece.
Moutsopoulos HM; Department of Pathophysiology, School of Medicine, National and Kapodestrian University of Athens, Greece.
Manoussakis MN; Department of Pathophysiology, School of Medicine, National and Kapodestrian University of Athens, Greece; Hellenic Pasteur Institute, Athens, Greece. Electronic address: menman@med.uoa.gr.

J Autoimmun ; 56: 12-22, 2015 Jan.

Article em En | MEDLINE | ID: mdl-25228497

Assuntos

Fagocitose/imunologia; Síndrome de Sjogren/sangue; Síndrome de Sjogren/imunologia; Adulto; Idoso; Artrite Reumatoide/imunologia; Autoanticorpos/sangue; Autoanticorpos/imunologia; Desoxirribonuclease I/sangue; Ativação Enzimática; Feminino; Granulócitos/imunologia; Humanos; Imunoglobulina G/sangue; Imunoglobulina G/imunologia; Lúpus Eritematoso Sistêmico/sangue; Lúpus Eritematoso Sistêmico/imunologia; Masculino; Pessoa de Meia-Idade; Monócitos/imunologia; Necrose/imunologia; Fagócitos/imunologia; Índice de Gravidade de Doença; Síndrome de Sjogren/diagnóstico

Palavras-chave

DNase1; Degradation of necrotic cell debris; Necrotic cell debris; Sjögren's syndrome; Systemic lupus erythematosus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fagocitose / Síndrome de Sjogren Tipo de estudo: Diagnostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Autoimmun Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Grécia

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