Super-resolution reconstruction of late gadolinium-enhanced MRI for improved myocardial scar assessment.
J Magn Reson Imaging
; 42(1): 160-7, 2015 Jul.
Article
em En
| MEDLINE
| ID: mdl-25236764
ABSTRACT
PURPOSE:
To develop and validate a method for improving image resolution of late gadolinium-enhanced (LGE) magnetic resonance imaging (MRI) for accurate assessment of myocardial scar. MATERIALS ANDMETHODS:
In a cohort of 37 postinfarction patients, LGE was performed prior to ventricular tachycardia catheter ablation therapy at 1.5T. A super-resolution reconstruction (SRR) technique was applied to the three anisotropic views short-axis (SA), two-chamber, and four-chamber, to reconstruct a single isotropic volume. For compensation of the interscan heart motion, a joint localized gradient-correlation-based scheme was developed. Scar was identified as either core or gray zone in both the SRR and original SA volumes, and evaluated based on the clinically established bipolar voltage range of the in vivo electroanatomical voltage mapping (EAVM).RESULTS:
Compared to the SA volume, the SRR method resulted in significantly (P < 0.05) reduced myocardial scar gray zone sizes (10.5 ± 8.8 g vs. 9.2 ± 8.1 g) and improved agreement of the bipolar voltage range of scar gray zone (0.99 ± 0.65 mV vs. 1.46 ± 1.15 mV).CONCLUSION:
We propose an SRR method to automatically reconstruct a high-quality isotropic LGE volume from three orthogonal views. Analysis of the in vivo EAVM demonstrated improved myocardial scar assessment from the SRR volume compared with the SA LGE alone.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Interpretação de Imagem Assistida por Computador
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Aumento da Imagem
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Cicatriz
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Miocárdio Atordoado
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Gadolínio DTPA
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Imageamento Tridimensional
Tipo de estudo:
Diagnostic_studies
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Prognostic_studies
Limite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Magn Reson Imaging
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Holanda