p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1.

Tian, JinBin; Tep, Chhavy; Benedick, Alex; Saidi, Nabila; Ryu, Jae Cheon; Kim, Mi Lyang; Sadasivan, Shankar; Oberdick, John; Smeyne, Richard; Zhu, Michael X; Yoon, Sung Ok

Tian, JinBin; Tep, Chhavy; Benedick, Alex; Saidi, Nabila; Ryu, Jae Cheon; Kim, Mi Lyang; Sadasivan, Shankar; Oberdick, John; Smeyne, Richard; Zhu, Michael X; Yoon, Sung Ok.

Afiliação

Tian J; the Department of Neuroscience, Ohio State University, Columbus, Ohio 43210, the Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas 77030.
Tep C; From the Department of Molecular and Cellular Biochemistry, the Biochemistry Program, and.
Benedick A; From the Department of Molecular and Cellular Biochemistry.
Saidi N; From the Department of Molecular and Cellular Biochemistry.
Ryu JC; From the Department of Molecular and Cellular Biochemistry.
Kim ML; From the Department of Molecular and Cellular Biochemistry.
Sadasivan S; the Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, and.
Oberdick J; the Biochemistry Program, and.
Smeyne R; the Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, and.
Zhu MX; the Department of Neuroscience, Ohio State University, Columbus, Ohio 43210, the Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas 77030 michael.x.zhu@uth.tmc.edu.
Yoon SO; From the Department of Molecular and Cellular Biochemistry, sung.yoon@osumc.edu.

J Biol Chem ; 289(45): 31458-72, 2014 Nov 07.

Article em En | MEDLINE | ID: mdl-25253694

Assuntos

Cerebelo/metabolismo; Neuropeptídeos/metabolismo; Células de Purkinje/metabolismo; Receptores de Fator de Crescimento Neural/metabolismo; Proteínas rac1 de Ligação ao GTP/metabolismo; Animais; Eletrofisiologia; Complexo de Golgi/metabolismo; Glicoproteínas de Membrana/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Microscopia Eletrônica; Técnicas de Patch-Clamp; Canais de Potássio/metabolismo; Proteínas Tirosina Quinases/metabolismo; Transdução de Sinais; Canais de Potássio Ativados por Cálcio de Condutância Baixa/metabolismo; Sinaptossomos/metabolismo; Tetraetilamônio/química; Proteínas rac de Ligação ao GTP/metabolismo

Palavras-chave

Brain-derived Neurotrophic Factor (BDNF); Cerebellum; Patch Clamp; Potassium Channel; Purkinje Cells; Rac1; SK Channels; p75 Neurotrophin Receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células de Purkinje / Neuropeptídeos / Cerebelo / Receptores de Fator de Crescimento Neural / Proteínas rac1 de Ligação ao GTP Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2014 Tipo de documento: Article

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