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PET imaging of ß-glucuronidase activity by an activity-based 124I-trapping probe for the personalized glucuronide prodrug targeted therapy.
Su, Yu-Cheng; Cheng, Ta-Chun; Leu, Yu-Ling; Roffler, Steve R; Wang, Jaw-Yuan; Chuang, Chih-Hung; Kao, Chien-Han; Chen, Kai-Chuan; Wang, Hsin-Ell; Cheng, Tian-Lu.
Afiliação
  • Su YC; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan. Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
  • Cheng TC; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
  • Leu YL; Department of Pharmacy, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.
  • Roffler SR; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
  • Wang JY; Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Chuang CH; Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan.
  • Kao CH; Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Chen KC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
  • Wang HE; Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan. tlcheng@kmu.edu.tw hewang@ym.edu.tw.
  • Cheng TL; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan. Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan. Center for Biomarkers and Biotech Drugs, Kaohsiung Medical University, Kaohsiung, Taiwan. tlcheng@kmu.edu
Mol Cancer Ther ; 13(12): 2852-63, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25277385
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Glucuronídeos / Tomografia por Emissão de Pósitrons / Glucuronidase / Radioisótopos do Iodo Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Glucuronídeos / Tomografia por Emissão de Pósitrons / Glucuronidase / Radioisótopos do Iodo Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Taiwan