The role of opioid receptors in migration and wound recovery in vitro in cultured human keratinocytes and fibroblasts.
Methods Mol Biol
; 1230: 273-7, 2015.
Article
em En
| MEDLINE
| ID: mdl-25293334
ABSTRACT
We have previously described significant changes in skin differentiation and the delay in wound healing from delta-opioid receptor knockout mice. In addition, we have shown that opioid receptor ligands and their receptor systems affect wound healing in vitro and the migration pattern of human skin cells, such as keratinocytes and fibroblasts (Bigliardi-Qi et al., Differentiation 74174-185, 2006; Bigliardi et al., Exp Dermatol 18424-430, 2009; Bigliardi et al., J Recept Signal Transduct Res 22191-199, 2002). This observation is true for both primary keratinocytes and fibroblasts derived from foreskin or normal human skin as well as for immortalized cell lines such as HaCaT cells.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Técnicas In Vitro
/
Movimento Celular
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Receptores Opioides delta
Limite:
Animals
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Humans
Idioma:
En
Revista:
Methods Mol Biol
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2015
Tipo de documento:
Article