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RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.
Lauriol, Jessica; Keith, Kimberly; Jaffré, Fabrice; Couvillon, Anthony; Saci, Abdel; Goonasekera, Sanjeewa A; McCarthy, Jason R; Kessinger, Chase W; Wang, Jianxun; Ke, Qingen; Kang, Peter M; Molkentin, Jeffery D; Carpenter, Christopher; Kontaridis, Maria I.
Afiliação
  • Lauriol J; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Keith K; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Jaffré F; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Couvillon A; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Saci A; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Goonasekera SA; Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Howard Hughes Medical Institute, Cincinnati, OH 45229, USA.
  • McCarthy JR; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
  • Kessinger CW; Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
  • Wang J; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Ke Q; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Kang PM; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Molkentin JD; Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Howard Hughes Medical Institute, Cincinnati, OH 45229, USA.
  • Carpenter C; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
  • Kontaridis MI; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. mkontari@bidmc.harvard.edu.
Sci Signal ; 7(348): ra100, 2014 Oct 21.
Article em En | MEDLINE | ID: mdl-25336613
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Proteínas rho de Ligação ao GTP / Sistema de Sinalização das MAP Quinases / Miócitos Cardíacos / Fibrose Endomiocárdica / Insuficiência Cardíaca Limite: Animals Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Proteínas rho de Ligação ao GTP / Sistema de Sinalização das MAP Quinases / Miócitos Cardíacos / Fibrose Endomiocárdica / Insuficiência Cardíaca Limite: Animals Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos