Oleic acid content of a meal promotes oleoylethanolamide response and reduces subsequent energy intake in humans.
Food Funct
; 6(1): 204-10, 2015 Jan.
Article
em En
| MEDLINE
| ID: mdl-25347552
ABSTRACT
Animal data suggest that dietary fat composition may influence endocannabinoid (EC) response and dietary behavior. This study tested the hypothesis that fatty acid composition of a meal can influence the short-term response of ECs and subsequent energy intake in humans. Fifteen volunteers on three occasions were randomly offered a meal containing 30 g of bread and 30 mL of one of three selected oils sunflower oil (SO), high oleic sunflower oil (HOSO) and virgin olive oil (VOO). Plasma EC concentrations and appetite ratings over 2 h and energy intake over 24 h following the experimental meal were measured. Results showed that after HOSO and VOO consumption the circulating oleoylethanolamide (OEA) was significantly higher than after SO consumption; a concomitantly significant reduction of energy intake was found. For the first time the oleic acid content of a meal was demonstrated to increase the post-prandial response of circulating OEA and to reduce energy intake at subsequent meals in humans.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Regulação do Apetite
/
Óleos de Plantas
/
Ingestão de Energia
/
Ácidos Oleicos
/
Ácido Oleico
/
Endocanabinoides
/
Desjejum
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Food Funct
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Itália