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Identification of a novel 2-pyridyl-benzensulfonamide derivative, RQ-00203078, as a selective and orally active TRPM8 antagonist.
Ohmi, Masashi; Shishido, Yuji; Inoue, Tadashi; Ando, Kazuo; Fujiuchi, Akiyoshi; Yamada, Akiko; Watanabe, Shuzo; Kawamura, Kiyoshi.
Afiliação
  • Ohmi M; Research and Development, RaQualia Pharma Inc., 5-2 Taketoyo, Aichi 470-2341, Japan. Electronic address: masashi.ohmi@raqualia.com.
  • Shishido Y; Research and Development, RaQualia Pharma Inc., 5-2 Taketoyo, Aichi 470-2341, Japan.
  • Inoue T; Research and Development, RaQualia Pharma Inc., 5-2 Taketoyo, Aichi 470-2341, Japan.
  • Ando K; Research and Development, RaQualia Pharma Inc., 5-2 Taketoyo, Aichi 470-2341, Japan.
  • Fujiuchi A; Research and Development, RaQualia Pharma Inc., 5-2 Taketoyo, Aichi 470-2341, Japan.
  • Yamada A; Research and Development, RaQualia Pharma Inc., 5-2 Taketoyo, Aichi 470-2341, Japan.
  • Watanabe S; Research and Development, RaQualia Pharma Inc., 5-2 Taketoyo, Aichi 470-2341, Japan.
  • Kawamura K; Research and Development, RaQualia Pharma Inc., 5-2 Taketoyo, Aichi 470-2341, Japan. Electronic address: kiyoshi.kawamura@raqualia.com.
Bioorg Med Chem Lett ; 24(23): 5364-8, 2014 Dec 01.
Article em En | MEDLINE | ID: mdl-25455182
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canais de Cátion TRPM Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canais de Cátion TRPM Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article