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Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.
Würtz, Peter; Wang, Qin; Kangas, Antti J; Richmond, Rebecca C; Skarp, Joni; Tiainen, Mika; Tynkkynen, Tuulia; Soininen, Pasi; Havulinna, Aki S; Kaakinen, Marika; Viikari, Jorma S; Savolainen, Markku J; Kähönen, Mika; Lehtimäki, Terho; Männistö, Satu; Blankenberg, Stefan; Zeller, Tanja; Laitinen, Jaana; Pouta, Anneli; Mäntyselkä, Pekka; Vanhala, Mauno; Elliott, Paul; Pietiläinen, Kirsi H; Ripatti, Samuli; Salomaa, Veikko; Raitakari, Olli T; Järvelin, Marjo-Riitta; Smith, George Davey; Ala-Korpela, Mika.
Afiliação
  • Würtz P; Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
  • Wang Q; Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
  • Kangas AJ; Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
  • Richmond RC; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.
  • Skarp J; Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland.
  • Tiainen M; Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
  • Tynkkynen T; Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
  • Soininen P; Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
  • Havulinna AS; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.
  • Kaakinen M; Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Viikari JS; Department of Medicine, University of Turku and Turku University Hospital, Turku, Finland.
  • Savolainen MJ; Department of Internal Medicine, Clinical Research Center and Biocenter Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland.
  • Kähönen M; Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland.
  • Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, Tampere, Finland.
  • Männistö S; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.
  • Blankenberg S; University Heart Center Hamburg, Hamburg, Germany.
  • Zeller T; University Heart Center Hamburg, Hamburg, Germany.
  • Laitinen J; Finnish Institute of Occupational Health, Helsinki, Finland.
  • Pouta A; Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland; Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland.
  • Mäntyselkä P; Primary Health Care, School of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
  • Vanhala M; Primary Health Care, School of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland; Primary Health Care, Central Finland Central Hospital, Jyväskylä, Finland.
  • Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom.
  • Pietiläinen KH; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland; Research Programs Unit Diabetes and Obesity, University of Helsinki, Helsinki, Finland.
  • Ripatti S; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Wellcome Trust Sanger Institute, Hinxton, United Kingdom; Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland.
  • Salomaa V; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.
  • Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
  • Järvelin MR; Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland; Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, Imperial College L
  • Smith GD; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.
  • Ala-Korpela M; Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Oulu University Hospital, Oulu,
PLoS Med ; 11(12): e1001765, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25490400
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peso Corporal / Adiposidade / Análise da Randomização Mendeliana Tipo de estudo: Clinical_trials / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Finlândia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peso Corporal / Adiposidade / Análise da Randomização Mendeliana Tipo de estudo: Clinical_trials / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Finlândia