[Status of the pituitary-adrenal system in patients with non- specific ulcerative colitis]. / Sostoianie gipofizarno-nadpochechnikovoi sistemy u bo'lnykh nespetsificheskim iazvennym kolitom.
Klin Med (Mosk)
; 67(5): 116-9, 1989 May.
Article
em Ru
| MEDLINE
| ID: mdl-2549298
ABSTRACT
The blood content of basal cortisol was studied in 54 patients with a total form of non-specific ulcerous colitis and in 23 of them that of ACTH. A low cortisol level was revealed in 71.4 per cent of the patients, while the level of ACTH remained unchanged. Treatment with prednisolone (1-2 mg/kg) for 6-9 weeks did not deteriorate the functional state of the hypophyseal-adrenal system. A single administration of the total daily dose of prednisolone in the morning protected the adrenal cortex from exhaustion and in some of the patients even caused increased in and normalization of the cortisol level. Rectal administration of hydrocortisone (125 mg), which was included in therapeutic scheme ensured normalization of the blood plasma cortisol level and did not cause decrease in the ACTH level.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sistema Hipófise-Suprarrenal
/
Colite Ulcerativa
Limite:
Adolescent
/
Adult
/
Humans
/
Middle aged
Idioma:
Ru
Revista:
Klin Med (Mosk)
Ano de publicação:
1989
Tipo de documento:
Article