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Golgi-located NTPDase1 of Leishmania major is required for lipophosphoglycan elongation and normal lesion development whereas secreted NTPDase2 is dispensable for virulence.
Sansom, Fiona M; Ralton, Julie E; Sernee, M Fleur; Cohen, Alice M; Hooker, David J; Hartland, Elizabeth L; Naderer, Thomas; McConville, Malcolm J.
Afiliação
  • Sansom FM; Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, Victoria, Australia; Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia.
  • Ralton JE; Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, Victoria, Australia.
  • Sernee MF; Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, Victoria, Australia.
  • Cohen AM; Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, Victoria, Australia.
  • Hooker DJ; Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia.
  • Hartland EL; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
  • Naderer T; Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, Victoria, Australia.
  • McConville MJ; Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, Victoria, Australia.
PLoS Negl Trop Dis ; 8(12): e3402, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25521752
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apirase / Glicoesfingolipídeos / Antígenos CD / Leishmania major / Complexo de Golgi Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: PLoS Negl Trop Dis Assunto da revista: MEDICINA TROPICAL Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apirase / Glicoesfingolipídeos / Antígenos CD / Leishmania major / Complexo de Golgi Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: PLoS Negl Trop Dis Assunto da revista: MEDICINA TROPICAL Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália