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DNA polymerase ß deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.
Sykora, Peter; Misiak, Magdalena; Wang, Yue; Ghosh, Somnath; Leandro, Giovana S; Liu, Dong; Tian, Jane; Baptiste, Beverly A; Cong, Wei-Na; Brenerman, Boris M; Fang, Evandro; Becker, Kevin G; Hamilton, Royce J; Chigurupati, Soumya; Zhang, Yongqing; Egan, Josephine M; Croteau, Deborah L; Wilson, David M; Mattson, Mark P; Bohr, Vilhelm A.
Afiliação
  • Sykora P; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Misiak M; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA Laboratory of Neurosciences, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 212
  • Wang Y; Laboratory of Neurosciences, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Ghosh S; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Leandro GS; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA Laboratory of Genetics, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, U
  • Liu D; Laboratory of Neurosciences, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Tian J; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Baptiste BA; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Cong WN; Laboratory of Clinical Investigation, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Brenerman BM; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Fang E; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Becker KG; Department of Genetics, Ribeirao Preto Medical School, University of Sao Paulo-Ribeirao Preto, SP 14049-900, Brazil.
  • Hamilton RJ; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Chigurupati S; Laboratory of Neurosciences, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Zhang Y; Laboratory of Clinical Investigation, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Egan JM; Laboratory of Clinical Investigation, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Croteau DL; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Wilson DM; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Mattson MP; Laboratory of Neurosciences, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA.
  • Bohr VA; Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD 21224, USA vbohr@nih.gov.
Nucleic Acids Res ; 43(2): 943-59, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25552414
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Polimerase beta / Reparo do DNA / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Polimerase beta / Reparo do DNA / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos