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Scl binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence.
Org, Tõnis; Duan, Dan; Ferrari, Roberto; Montel-Hagen, Amelie; Van Handel, Ben; Kerényi, Marc A; Sasidharan, Rajkumar; Rubbi, Liudmilla; Fujiwara, Yuko; Pellegrini, Matteo; Orkin, Stuart H; Kurdistani, Siavash K; Mikkola, Hanna Ka.
Afiliação
  • Org T; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA.
  • Duan D; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA.
  • Ferrari R; Department of Biological Chemistry, University of California, Los Angeles, CA, USA Eli and Edythe Broad Stem Cell Research Center, University of California, Los Angeles, CA, USA.
  • Montel-Hagen A; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA.
  • Van Handel B; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA.
  • Kerényi MA; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute Harvard Stem Cell Institute Harvard Medical School, Boston, MA, USA.
  • Sasidharan R; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA.
  • Rubbi L; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA.
  • Fujiwara Y; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute Harvard Stem Cell Institute Harvard Medical School, Boston, MA, USA.
  • Pellegrini M; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA.
  • Orkin SH; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Hematology/Oncology, Children's Hospital Boston, Howard Hughes Medical Institute Harvard Stem Cell Institute Harvard Medical School, Boston, MA, USA.
  • Kurdistani SK; Department of Biological Chemistry, University of California, Los Angeles, CA, USA Eli and Edythe Broad Stem Cell Research Center, University of California, Los Angeles, CA, USA.
  • Mikkola HK; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA Eli and Edythe Broad Stem Cell Research Center, University of California, Los Angeles, CA, USA hmikkola@mcdb.ucla.edu.
EMBO J ; 34(6): 759-77, 2015 Mar 12.
Article em En | MEDLINE | ID: mdl-25564442
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Diferenciação Celular / Proteínas Proto-Oncogênicas / Elementos Facilitadores Genéticos / Regulação da Expressão Gênica no Desenvolvimento / Mioblastos Cardíacos / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Mesoderma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: EMBO J Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Diferenciação Celular / Proteínas Proto-Oncogênicas / Elementos Facilitadores Genéticos / Regulação da Expressão Gênica no Desenvolvimento / Mioblastos Cardíacos / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Mesoderma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: EMBO J Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos