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Using negative pressure wound therapy on microskin autograft wounds.
Zhang, Fang; Lv, Kai-Yang; Qiu, Xiao-Chen; Luo, Peng-Fei; Zheng, Xing-Feng; Zhu, Shi-Hui; Xia, Zhao-Fan.
Afiliação
  • Zhang F; Department of Burn Surgery, The Second Military Medical University affiliated Changhai Hospital, Shanghai, China; No.73901 Troop of PLA, Shanghai, China.
  • Lv KY; Department of Burn Surgery, The Second Military Medical University affiliated Changhai Hospital, Shanghai, China.
  • Qiu XC; Department of Burns & Plastic Surgery, 309th Hospital of PLA, Beijing, China.
  • Luo PF; Department of Burn Surgery, The Second Military Medical University affiliated Changhai Hospital, Shanghai, China.
  • Zheng XF; Department of Burn Surgery, The Second Military Medical University affiliated Changhai Hospital, Shanghai, China.
  • Zhu SH; Department of Burn Surgery, The Second Military Medical University affiliated Changhai Hospital, Shanghai, China. Electronic address: doctorzhushihui@163.com.
  • Xia ZF; Department of Burn Surgery, The Second Military Medical University affiliated Changhai Hospital, Shanghai, China. Electronic address: xiazhaofan@163.com.
J Surg Res ; 195(1): 344-50, 2015 May 01.
Article em En | MEDLINE | ID: mdl-25586332
ABSTRACT

BACKGROUND:

Microskin autografts with conventional wrap and compression are used extensively in the treatment of skin and tissue defects. This comparative study aimed at investigation of the clinical application of negative pressure wound therapy (NPWT) in combination with microskin autografts for repair of acute and chronic wounds.

METHODS:

A prospective case-control study was performed from December 1, 2010-December 31, 2013 in Changhai Hospital, Shanghai. We compared a study group of patients received microskin autografting covered by NPWT with that of a control group of patients received microskin autografting covered by a conventional gauze.

RESULTS:

A total of 81 patients were in this study, 27 patients were allocated to the study group and 54 patients to the control group. The study group exhibited significant low infection rate and pain score during removal of inner layer at first dressing change after skin grafting compared with those of the control group (P < 0.05). The time interval between skin grafting and first postoperative change was longer in the study group than that in the control group (P < 0.01), the study group showed a significant shorter 95% wound healing time (P < 0.05), and survival rate of microskin autografts in the study group was higher than that in the control group (P < 0.05).

CONCLUSIONS:

NPWT is beneficial for wound closure after microskin autografts, which prolongs the interval between skin transplantation and first postoperative dressing change, reduces pain during removal of inner layer dressing, increases skin graft survival rate, and shortens wound healing time. Therefore, NPWT can be recommended for repair of acute and chronic wounds with microskin autografts.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Pele / Tratamento de Ferimentos com Pressão Negativa Tipo de estudo: Clinical_trials / Observational_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Surg Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Pele / Tratamento de Ferimentos com Pressão Negativa Tipo de estudo: Clinical_trials / Observational_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Surg Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China